Process Biotechnology (Theory and Practice)

There has been rapid advancement in the field of process biotechnology during the past five decades. It has expanded in fundamental and experimental aspects and is growing further in terms of biochemical engineering and biotechnology. Theory and practice are still keywords in all research-based teaching and learning, and process biotechnology is no exception.

For teaching research-based subjects in academic institutions, universities, and colleges and handling problems in biotechnology industry, the author has written a few other books, including Advanced Process Biotechnology and Experimental Process Biotechnology Protocols. However, it is essential for beginners to have exposure to tutorials and design calculations. This book provides undergraduates, postgraduates, and pre-PhD students with a scope to understand theory-based numerical aspects of process biotechnology.

The field of process biotechnology has become more promising as many government, private, and multinational organizations have opened new scopes for biochemical engineering, biotechnology, and related areas. Thus, the need to provide scholars and teachers with relevant and comprehensive knowledge resource has become a necessity. In this regard, the author hopes that this book will be a comprehensive practice treatise for learners.

This book is divided into two sections, comprising four chapters in each section. Section I refreshes the theoretical background to a large extent within the first four chapters. Section II deals with bioprocess engineering tutorials with many model problems and solutions for candidates to practice.

1. Prebiotic Science of Chemicals for Life

1.1 Introduction

1.2 Timescale of Terrestrial Evolution

1.3 Heat Death in Cosmos

1.4 Modern Biochemical Engineering and Biotechnology

Viewpoints of Evolution of Life Forms

1.5 Ecology and Environment

1.6 Asymbiotic Non-rhizobial MPI in Eco-biotechnology

1.7 Overproducer Regenerated Plants

1.8 Human Body Design Evolution

1.9 Importance of Updated Human Body Design

1.10 Conclusion



2. Biotic Chemistry

2.1 Introduction

2.2 Hydrogen Bond

2.3 Water

2.4 Biochemistry and Immunochemistry: A Concise Treatise

2.5 Protein Kinesis Engineering

2.6 Tutorial Problem



3. Cell Biology and Microbiology

3.1 Definition of a Biocell

3.2 Biocell Types, Positioning, Characteristics, and Identification Tests

3.3 Biocellular Design and Activity

3.4 Archaebacteria: The Newer Biocells

3.5 Ultrastructural Features

3.6 Yeasts

3.7 Cell and Tissue System Biology

3.8 Cellular Materials and Metabolism in Biotechnology

3.9 Microbes and Microbiology



4. Chemical and Biochemical Engineering Principles

4.1 Units and Dimensions

4.2 Dimensional Analysis

4.3 Fundamentals of Material Balance

4.4 Concept of Modelling of Biological Reaction Systems

4.5 Fluid Statics and Applications

4.6 Fluid Flow Phenomena: Viscosity and the Momentum Flux

4.7 Weirs

4.8 Laminar and Turbulent Flows

4.9 Basic Equations of Fluid Flow

4.10 Mass Transfer Principles

4.11 Mass Transfer Principles Advances

4.12 Heat Transfer by Conduction

4.13 Tutorials

4.14 Heat Transfer by Convection

4.15 Heat Transfer by Radiation

4.16 Evaporation

4.17 Refrigeration

4.18 Heat Exchangers

4.19 Adsorption

4.20 Extraction

4.21 Leaching and Bioleaching

4.22 Distillation

4.23 Drying of Biological Products

4.24 Freeze Drying of Biological Materials

4.25 Automatic Process Control Principles

4.26 Properties and Functions of Polymeric and Biopolymeric Engineering Materials

4.27 Basic of Computer and Its Use in Biosystems

4.28 Genetic Engineering Principles and Considerations in Handling

Recombinant Cells in Large Scale

4.29 Modern Instrumental Techniques in Process Biotechnology



Section II: Bioprocess Engineering System: tutorials

5. Upstream Process Biotechnology: Solved Numerical Problems

5.1 Pure Culture Microbial Biotechnology

5.2 Mixed Culture Microbial Biotechnology

5.3 Immobilized/Anchored Biosystems



6. Enzyme Engineering and Technology: Solved Numerical Problems

6.1 Enzyme Kinetics

6.2 Enzyme Reactors

6.3 Enzyme Production Strategies


7. Product Recovery and Purification: Solved Numerical Problems

7.1 Introduction

7.2 Filtration

7.3 Ultrafiltration

7.4 Reverse Osmosis

7.5 Foam Fractionation

7.6 Adsorption

7.7 Extraction

7.8 Novel Bioproduct Recovery Design Problem

7.9 Possible Contaminants

8. Unsolved Numerical Problems

8.1 Microbial Cell System

8.2 Reactor Kinetics and Stability

8.3 Plant Cell System

8.4 Animal Cell System

8.5 Miscellaneous Biosystems



About the Author

Answer Keys